Anti Anxiety Meds for Dogs: Pros, Cons & Alternatives

Common signs include:

• Excessive barking, whining, or howling
  
  

• Destructive behavior (chewing, digging, scratching)
  
  

• Pacing, trembling, or hiding
  
  

• Changes in appetite or bathroom habits
  
  

• Restlessness or escape attempts
  
  

Physical signs like panting, drooling, or shedding may also appear. Spotting symptoms early allows you to consult your vet and create a plan for relief.

Veterinarians often prescribe:

• SSRIs (e.g., fluoxetine)
  
  

• TCAs (e.g., clomipramine)
  
  

• Benzodiazepines (e.g., alprazolam, diazepam)
  
  

• Adjuncts like trazodone or gabapentin
  
  

Your vet will determine the best option based on your dog’s size, health, and type of anxiety.

• Effective Symptom Relief: Medications can quickly reduce destructive behavior and restlessness.
  
  

• Supports Training: By lowering anxiety, dogs become more receptive to behavior modification and positive reinforcement.
  
  

For guidance on how medication supports training, review  ASPCA’s dog behavior and anxiety resources.

While effective, medications carry potential downsides. Common side effects include:

• Drowsiness, loss of appetite, or upset stomach
  
  

• Increased thirst or drooling
  
  

• Restlessness or tremors
  
  

Long-term use may affect the liver or kidneys, and abrupt withdrawal from certain drugs can cause withdrawal symptoms. Always follow your vet’s guidance and schedule regular checkups.

Read more about  safe use of dog anxiety medication on PetMD.

Techniques like desensitization and counterconditioning help dogs build coping skills. Positive reinforcement and consistent routines support calm behavior.
For practical training strategies, see Humane Society’s tips for managing anxious dogs.

Common options include:

• L-theanine, tryptophan, valerian root, melatonin
  
  

•  CBD oil or  chews (vet-approved and THC-free)
  
  

• Pheromone diffusers, chamomile chews, or weighted vests
  
  

Always check with your vet before adding supplements.

• Create a safe space with familiar items
  
  

• Maintain consistent routines
  
  

• Use mental enrichment like puzzle toys
  
  

• Play calming music or white noise
  
  

These small adjustments can significantly lower anxiety levels.

Consider medication if your dog’s anxiety:

• Causes self-harm or aggression
  
  

• Disrupts daily life
  
  

• Doesn’t improve with training or supplements
  
  

For mild anxiety, start with natural methods and environmental support. Your vet can help decide if medication or a combination approach is best.

1. What is the best anti anxiety medicine for dogs?
Commonly prescribed options include fluoxetine, clomipramine, and trazodone. The best choice depends on your dog’s health, anxiety type, and severity.

2. Can I give my dog human anxiety medication?
No — human medications can be toxic to dogs. Always use prescriptions approved by your veterinarian.

3. Are natural calming supplements safe for dogs?
Yes, when vet-approved and properly dosed. Supplements like L-theanine, melatonin, and CBD are often used for mild anxiety.

Helping your dog overcome anxiety takes patience and informed care. Anti anxiety meds for dogs—such as SSRIs, TCAs, and benzodiazepines—can bring relief for severe cases but work best when combined with training and lifestyle improvements.

For mild to moderate anxiety,  natural alternatives like calming supplements, pheromones, and behavioral therapy can offer safe, effective relief. Always consult your veterinarian to tailor a plan to your dog’s unique needs.

With consistent support, positive routines, and expert guidance, even anxious dogs can rediscover calm, confidence, and joy.